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AMB-FUBINACA buy online (also known as FUB-AMB and MMB-FUBINACA) is an indazole-based synthetic cannabinoid. That is a potent agonist for the cannabinoid receptors, with Ki values of 10.04 nM at CB1 and 0.786 nM at CB2 and EC50 values of 0.5433 nM at CB1 and 0.1278 nM at CB2. And has been sol’d online as a designer drug.
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors. Also known as the endocannabinoid system in cells that alter neurotransmitter release in the brain. Ligands for these receptor proteins include the endocannabinoids produced naturally in the body by animals; phytocannabinoids, found in cannabis and some other plants; and synthetic cannabinoids, manufactured artificially.
The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC). The primary psychoactive compound in cannabis.Cannabidiol (CBD) is another major constituent of the plant. There are at least 113 different cannabinoids isolate from cannabis, exhibiting varied effects. Synthetic cannabinoids encompass a variety of distinct chemical classes: the classical cannabinoids structurally related to THC, the nonclassical cannabinoids (cannabimimetics) including the aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, and arylsulfonamides as well as eicosanoids related to endocannabinoids. Buy AMB-FUBINACA Online
Medical uses include the treatment o
f nausea due to chemotherapy, spasticity, and possibly neuropathic pain. Common side effects include dizziness, sedation, confusion, dissociation and “feeling high”.
Before the 1980s, it was often speculate that cannabinoids produced their physiological and behavioral effects via nonspecific interaction with cell membranes. Instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. These receptors are common in animals, and have been found in mammals, birds, fish, and reptiles. At present, there are two know types of cannabinoid receptors, termed CB1 and CB2,with mounting evidence of more. The human brain has more cannabinoid receptors than any other G protein-coupled receptor (GPCR) type.
They are also found in the cerebellum and in both male and female reproductive systems. CB1 receptors are absent in the medulla oblongata, the part of the brain stem responsible for respiratory and cardiovascular functions. While found only in the peripheral nervous system, a report does indicate that CB2 is expressed by a subpopulation of microglia in the human cerebellum. CB2 receptors appear to be responsible for the anti-inflammatory and possibly other therapeutic effects of cannabis seen in animal models.Buy AMB-FUBINACA Online