Methiopropamine (MPA)April 29, 2019
Methiopropamine (MPA), a new psychoactive substance (NPS), is a stimulant drug. Sold on its own or within a range of branded products.
It’s a thiophene ring-based structural analogue of methamphetamine which was originally reported in 1942.Chemically, it is not a phenethylamine or amphetamine, nor is it their functional analog.
Methiopropamine (MPA) is a stimulant (upper) drug with similar effects to methamphetamine which can make you feel alert and more energetic. It also increases your heart rate and breathing. People using it can experience a mild high. Sexual arousal and loss of appetite as well as difficulty urinating (peeing), chest pain, breathing problems and an urge to re-dose.
Methiopropamine functions as a selective norepinephrine-dopamine releasing agent. This allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects. It is approximately one third as potent as dextroamphetamine as a norepinephrine reuptake inhibitor and one fifth as much as a dopamine reuptake inhibitor. It displays negligible activity as a serotonin reuptake inhibitor.
Side effects About Methiopropamine (MPA)
Stimulation – In terms of its effects on the physical energy levels of the user. Methiopropamine is usually consideredd to be mildly to moderately energetic and stimulating in a fashion. That is considerably weaker in comparison to that of traditional recreational stimulants such as amphetamine, MDMA or cocaine. This encourages physical activities such as performing chores, repetitive tasks which would otherwise be boring and strenuous physical activities.
Spontaneous tactile sensations – The “body high” of methiopropamine can be describe as an intense euphoric, sharp and all-encompassing tingling sensation that remains present through the duration of the experience.
Increased heart rate. In comparison to other stimulants such as amphetamine or cocaine, methiopropamine only has a mild effect on one’s heart rate.
Appetite suppression The above components are also accompanied by a suppression of appetite. Which is usually much less intense in strength in comparison to the appetite suppression experienced with amphetamine or methamphetamine.
Temperature regulation suppression
Teeth grinding – This component can be considere to be less intense when compare with that of MDMA.
MPA is described by many users as being similar to drugs such as caffeine or methylphenidate (Ritalin) and users state that they find it helpful when studying or working late. MPA reportedly induces very little euphoria. Comedown effects are usually describe as minimal compare to some other substances, with effects including tiredness, low mood, headaches and irritability.
Although many psychoactive substances are safe on their own, they can become dangerous and even life-threatening when combined with other substances. The list below contains some common potentially dangerous combinations, but may not include all of them. Certain combinations may be safe in low doses of each but still increase the potential risk of death. Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.
Stimulants – MPA can be potentially dangerous in combination with other stimulants as it can increase one’s heart rate and blood pressure to dangerous levels.
25x-NBOMe – Both the NBOMe series and this compound induce powerful stimulation and their interaction may cause severe side effects. These can include thought loops, seizures, increased blood pressure, vasoconstriction, increased heart rate, and heart failure (in extreme cases).
Alcohol – It is dangerous to combine alcohol, a depressant, with stimulants due to the risk of excessive intoxication. Stimulants decrease the sedative effect of alcohol which is the main factor most people consider when determining their level of intoxication. Once the stimulant wears off, the effects of alcohol will be significantly increased. Leading to intensified disinhibition as well as respiratory depression.